ctcRbase

Entry Detail

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General Information

Database ID: BRCA00734 Cancer Type: breast cancer Dataset: GSE109761 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: NFKBIA Full Name: NFKB inhibitor alpha Category: mRNA Synonyms: EDAID2|IKBA|MAD-3|NFKBI Chromosome: chr14 Strand: - Coordinate: Start Site(bp): 35401511 End Site(bp): 35404749 Gene Summary: This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease. [provided by RefSeq, Aug 2011] External Links: Ensembl ID: ENSG00000100906 HGNC ID: HGNC:7797 Entrez Gene: 4792

Expression Profile of NFKBIA Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-129-5p YES YES NO hsa-miR-196a-5p YES YES NO hsa-miR-196b-5p YES YES NO hsa-miR-208a-3p YES YES NO hsa-miR-208b-3p YES YES NO hsa-miR-300 YES YES YES hsa-miR-34a-5p YES YES NO hsa-miR-34c-5p YES YES NO hsa-miR-381-3p YES YES YES hsa-miR-449a YES YES NO hsa-miR-449b-5p YES YES NO Display: