ctcRbase

Entry Detail

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General Information

Database ID: BRCA00741 Cancer Type: breast cancer Dataset: GSE109761 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: PABPC1 Full Name: poly(A) binding protein cytoplasmic 1 Category: mRNA Synonyms: PAB1|PABP|PABP1|PABPC2|PABPL1 Chromosome: chr8 Strand: - Coordinate: Start Site(bp): 100685816 End Site(bp): 100722809 Gene Summary: This gene encodes a poly(A) binding protein. The protein shuttles between the nucleus and cytoplasm and binds to the 3' poly(A) tail of eukaryotic messenger RNAs via RNA-recognition motifs. The binding of this protein to poly(A) promotes ribosome recruitment and translation initiation; it is also required for poly(A) shortening which is the first step in mRNA decay. The gene is part of a small gene family including three protein-coding genes and several pseudogenes.[provided by RefSeq, Aug 2010] External Links: Ensembl ID: ENSG00000070756 HGNC ID: HGNC:8554 Entrez Gene: 26986

Expression Profile of PABPC1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-101-3p YES YES NO hsa-miR-128-3p YES YES NO hsa-miR-129-5p YES YES YES hsa-miR-1-3p YES YES NO hsa-miR-144-3p YES YES NO hsa-miR-181a-5p YES YES NO hsa-miR-181b-5p YES YES NO hsa-miR-181c-5p YES YES NO hsa-miR-181d-5p YES YES NO hsa-miR-186-5p YES YES YES hsa-miR-206 YES YES NO hsa-miR-374a-5p YES YES YES hsa-miR-374b-5p YES YES YES hsa-miR-423-3p YES NO YES hsa-miR-452-5p YES NO YES hsa-miR-543 YES YES NO hsa-miR-599 YES YES NO hsa-miR-613 YES YES NO Display: