ctcRbase

Entry Detail

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General Information

Database ID: BRCA00776 Cancer Type: breast cancer Dataset: GSE109761 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: HNRNPK Full Name: heterogeneous nuclear ribonucleoprotein K Category: mRNA Synonyms: AUKS|CSBP|HNRPK|TUNP Chromosome: chr9 Strand: - Coordinate: Start Site(bp): 83968083 End Site(bp): 83980616 Gene Summary: This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene is located in the nucleoplasm and has three repeats of KH domains that binds to RNAs. It is distinct among other hnRNP proteins in its binding preference; it binds tenaciously to poly(C). This protein is also thought to have a role during cell cycle progession. Several alternatively spliced transcript variants have been described for this gene, however, not all of them are fully characterized. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000165119 HGNC ID: HGNC:5044 Entrez Gene: 3190

Expression Profile of HNRNPK Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-10a-5p YES YES YES hsa-miR-10b-5p YES YES YES hsa-miR-1249-3p YES NO YES hsa-miR-129-5p YES YES YES hsa-miR-1-3p YES YES YES hsa-miR-153-3p YES YES YES hsa-miR-181a-5p YES NO YES hsa-miR-181b-5p YES NO YES hsa-miR-181c-5p YES NO YES hsa-miR-181d-5p YES NO YES hsa-miR-200b-3p YES YES YES hsa-miR-200c-3p YES YES YES hsa-miR-205-5p YES YES YES hsa-miR-206 YES YES YES hsa-miR-21-5p YES YES YES hsa-miR-219a-2-3p YES NO YES hsa-miR-28-5p YES YES YES hsa-miR-323a-3p YES NO YES hsa-miR-330-3p YES NO YES hsa-miR-339-5p YES YES YES hsa-miR-376c-3p YES YES YES hsa-miR-377-3p YES YES YES hsa-miR-384 YES YES YES hsa-miR-409-3p YES NO YES hsa-miR-429 YES YES YES hsa-miR-448 YES YES YES hsa-miR-495-3p YES YES NO hsa-miR-582-5p YES NO YES hsa-miR-590-5p YES YES YES hsa-miR-613 YES YES YES hsa-miR-653-5p YES YES NO hsa-miR-708-5p YES YES YES hsa-miR-873-5p YES YES YES Display: