ctcRbase

Entry Detail

---



General Information

Database ID: BRCA00797 Cancer Type: breast cancer Dataset: GSE41245 CTCs/CTM Isolation Method: CTC-Chip

Gene Information

ncRNA Symbol: RAD52 Full Name: RAD52 homolog, DNA repair protein Category: mRNA Synonyms: - Chromosome: chr12 Strand: - Coordinate: Start Site(bp): 912077 End Site(bp): 990053 Gene Summary: The protein encoded by this gene shares similarity with Saccharomyces cerevisiae Rad52, a protein important for DNA double-strand break repair and homologous recombination. This gene product was shown to bind single-stranded DNA ends, and mediate the DNA-DNA interaction necessary for the annealing of complementary DNA strands. It was also found to interact with DNA recombination protein RAD51, which suggested its role in RAD51 related DNA recombination and repair. A pseudogene of this gene is present on chromosome 2. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Jul 2014] External Links: Ensembl ID: ENSG00000002016 HGNC ID: HGNC:9824 Entrez Gene: 5893

Expression Profile of RAD52 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-185-5p YES YES NO hsa-miR-204-5p YES YES NO hsa-miR-211-5p YES YES NO hsa-miR-503-5p YES YES NO hsa-miR-542-3p YES YES NO hsa-miR-758-3p YES YES NO Display: