ctcRbase

Entry Detail

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General Information

Database ID: BRCA00883 Cancer Type: breast cancer Dataset: GSE111065 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: CLDN4 Full Name: claudin 4 Category: mRNA Synonyms: CPE-R|CPER|CPETR|CPETR1|WBSCR8|hCPE-R Chromosome: chr7 Strand: + Coordinate: Start Site(bp): 73799542 End Site(bp): 73832693 Gene Summary: The protein encoded by this intronless gene belongs to the claudin family. Claudins are integral membrane proteins that are components of the epithelial cell tight junctions, which regulate movement of solutes and ions through the paracellular space. This protein is a high-affinity receptor for Clostridium perfringens enterotoxin (CPE) and may play a role in internal organ development and function during pre- and postnatal life. This gene is deleted in Williams-Beuren syndrome, a neurodevelopmental disorder affecting multiple systems. [provided by RefSeq, Sep 2013] External Links: Ensembl ID: ENSG00000189143 HGNC ID: HGNC:2046 Entrez Gene: 1364

Expression Profile of CLDN4 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-24-3p YES YES NO hsa-miR-339-5p YES YES NO hsa-miR-455-3p YES NO YES hsa-miR-491-5p YES YES NO hsa-miR-541-3p YES NO NO hsa-miR-654-5p YES NO NO Display: