ctcRbase

Entry Detail

---



General Information

Database ID: BRCA00911 Cancer Type: breast cancer Dataset: GSE41245 CTCs/CTM Isolation Method: CTC-Chip

Gene Information

ncRNA Symbol: SNX6 Full Name: sorting nexin 6 Category: mRNA Synonyms: MSTP010|TFAF2 Chromosome: chr14 Strand: - Coordinate: Start Site(bp): 34561094 End Site(bp): 34630183 Gene Summary: This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein associates with the long isoform of the leptin receptor, the transforming growth factor-beta family of receptor serine-threonine kinases, and with receptor tyrosine kinases for platelet-derived growth factor, insulin, and epidermal growth factor. This protein may form oligomeric complexes with family member proteins through interactions of both the PX domain and the coiled coil regions of the molecules. Translocation of this protein from the cytoplasm to the nucleus occurs after binding to proviral integration site 1 protein. This gene results in two transcripts encoding two distinct isoforms. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000129515 HGNC ID: HGNC:14970 Entrez Gene: 58533

Expression Profile of SNX6 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-let-7a-5p YES YES YES hsa-let-7b-5p YES YES YES hsa-let-7c-5p YES YES YES hsa-let-7d-5p YES YES YES hsa-let-7e-5p YES YES YES hsa-let-7f-5p YES YES YES hsa-let-7g-5p YES YES YES hsa-let-7i-5p YES YES YES hsa-miR-124-3p YES YES NO hsa-miR-129-2-3p YES NO YES hsa-miR-146a-5p YES YES NO hsa-miR-146b-5p YES YES NO hsa-miR-155-5p YES YES NO hsa-miR-18a-5p YES YES NO hsa-miR-18b-5p YES YES NO hsa-miR-191-5p YES YES NO hsa-miR-199a-5p YES NO YES hsa-miR-199b-5p YES NO YES hsa-miR-200b-3p YES YES NO hsa-miR-200c-3p YES YES NO hsa-miR-223-3p YES YES NO hsa-miR-299-5p YES NO YES hsa-miR-30a-5p YES YES YES hsa-miR-30b-5p YES YES YES hsa-miR-30c-5p YES YES YES hsa-miR-30d-5p YES YES YES hsa-miR-30e-5p YES YES YES hsa-miR-330-3p YES NO YES hsa-miR-338-3p YES YES NO hsa-miR-33a-5p YES YES NO hsa-miR-33b-5p YES YES NO hsa-miR-340-5p YES YES NO hsa-miR-421 YES YES NO hsa-miR-487a-3p YES NO YES hsa-miR-495-3p YES YES NO hsa-miR-506-3p YES YES NO hsa-miR-98-5p YES YES YES Display: