ctcRbase

Entry Detail

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General Information

Database ID: BRCA00996 Cancer Type: breast cancer Dataset: GSE111065 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: SRSF5 Full Name: serine and arginine rich splicing factor 5 Category: mRNA Synonyms: HRS|SFRS5|SRP40 Chromosome: chr14 Strand: + Coordinate: Start Site(bp): 69726900 End Site(bp): 69772005 Gene Summary: The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016] External Links: Ensembl ID: ENSG00000100650 HGNC ID: HGNC:10787 Entrez Gene: 6430

Expression Profile of SRSF5 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-124-3p YES YES NO hsa-miR-181a-5p YES YES YES hsa-miR-181b-5p YES YES YES hsa-miR-181c-5p YES YES YES hsa-miR-181d-5p YES YES YES hsa-miR-28-5p NO YES YES hsa-miR-300 YES YES NO hsa-miR-320a YES YES NO hsa-miR-320b YES YES NO hsa-miR-320c YES YES NO hsa-miR-320d YES YES NO hsa-miR-340-5p YES YES NO hsa-miR-374a-5p YES YES NO hsa-miR-374b-5p YES YES NO hsa-miR-381-3p YES YES NO hsa-miR-383-5p NO YES YES hsa-miR-421 YES YES NO hsa-miR-495-3p YES YES YES hsa-miR-506-3p YES YES NO hsa-miR-543 YES YES NO hsa-miR-655-3p YES NO YES hsa-miR-708-5p NO YES YES Display: