ctcRbase

Entry Detail

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General Information

Database ID: BRCA01019 Cancer Type: breast cancer Dataset: GSE67939 CTCs/CTM Isolation Method: Cluster-Chip

Gene Information

ncRNA Symbol: RHOA Full Name: ras homolog family member A Category: mRNA Synonyms: ARH12|ARHA|RHO12|RHOH12 Chromosome: chr3 Strand: - Coordinate: Start Site(bp): 49359145 End Site(bp): 49412998 Gene Summary: This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants have been identified. [provided by RefSeq, Sep 2015] External Links: Ensembl ID: ENSG00000067560 HGNC ID: HGNC:667 Entrez Gene: 387

Expression Profile of RHOA Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-101-3p YES YES NO hsa-miR-128-3p YES YES NO hsa-miR-129-5p YES YES NO hsa-miR-140-3p YES NO YES hsa-miR-142-5p YES NO YES hsa-miR-144-3p YES YES NO hsa-miR-146a-5p YES YES NO hsa-miR-146b-5p YES YES NO hsa-miR-154-5p YES YES NO hsa-miR-185-5p YES YES NO hsa-miR-186-5p YES YES NO hsa-miR-194-5p YES YES NO hsa-miR-200b-3p YES YES YES hsa-miR-200c-3p YES YES YES hsa-miR-20a-5p YES YES NO hsa-miR-20b-5p YES YES NO hsa-miR-300 YES YES NO hsa-miR-330-5p YES YES NO hsa-miR-340-5p YES YES YES hsa-miR-361-5p YES YES YES hsa-miR-376a-3p YES YES NO hsa-miR-376b-3p YES YES NO hsa-miR-379-5p YES YES NO hsa-miR-381-3p YES YES NO hsa-miR-425-5p YES YES NO hsa-miR-429 YES YES YES hsa-miR-487a-3p YES NO YES hsa-miR-490-3p YES YES NO hsa-miR-519d-3p YES YES NO hsa-miR-542-3p YES YES NO hsa-miR-802 YES NO YES hsa-miR-93-5p YES YES NO Display: