ctcRbase

Entry Detail

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General Information

Database ID: BRCA01086 Cancer Type: breast cancer Dataset: GSE51827 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: YWHAZ Full Name: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta Category: mRNA Synonyms: 14-3-3-zeta|HEL-S-3|HEL-S-93|HEL4|KCIP-1|YWHAD Chromosome: chr8 Strand: - Coordinate: Start Site(bp): 100916525 End Site(bp): 100953388 Gene Summary: This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Several transcript variants that differ in the 5' UTR but that encode the same protein have been identified for this gene. [provided by RefSeq, Oct 2008] External Links: Ensembl ID: ENSG00000164924 HGNC ID: HGNC:12855 Entrez Gene: 7534

Expression Profile of YWHAZ Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-1224-5p YES NO YES hsa-miR-129-5p YES YES NO hsa-miR-134-5p YES YES YES hsa-miR-1-3p YES YES YES hsa-miR-140-3p YES NO YES hsa-miR-149-5p YES YES YES hsa-miR-155-5p YES YES YES hsa-miR-181a-5p YES YES YES hsa-miR-181b-5p YES YES YES hsa-miR-181c-5p YES YES YES hsa-miR-181d-5p YES YES YES hsa-miR-183-5p YES YES NO hsa-miR-185-5p YES YES YES hsa-miR-186-5p YES YES NO hsa-miR-188-5p YES NO YES hsa-miR-193a-3p YES YES YES hsa-miR-193b-3p YES YES YES hsa-miR-199a-3p YES NO YES hsa-miR-199b-3p YES NO YES hsa-miR-204-5p YES YES YES hsa-miR-206 YES YES YES hsa-miR-211-5p YES YES YES hsa-miR-214-3p YES YES NO hsa-miR-218-5p YES YES YES hsa-miR-22-3p YES YES YES hsa-miR-25-3p NO YES YES hsa-miR-28-5p YES YES YES hsa-miR-300 YES YES NO hsa-miR-302a-3p YES YES YES hsa-miR-302b-3p YES YES YES hsa-miR-302c-3p YES YES YES hsa-miR-302d-3p YES YES YES hsa-miR-302e YES YES YES hsa-miR-30a-5p YES YES YES hsa-miR-30b-5p YES YES YES hsa-miR-30c-5p YES YES YES hsa-miR-30d-5p YES YES YES hsa-miR-30e-5p YES YES YES hsa-miR-31-5p YES YES NO hsa-miR-320a YES YES NO hsa-miR-320b YES YES NO hsa-miR-320c YES YES NO hsa-miR-320d YES YES NO hsa-miR-32-5p NO YES YES hsa-miR-328-3p YES YES YES hsa-miR-339-5p YES YES YES hsa-miR-363-3p NO YES YES hsa-miR-367-3p NO YES YES hsa-miR-372-3p YES YES YES hsa-miR-373-3p YES YES YES hsa-miR-375 YES YES YES hsa-miR-381-3p YES YES NO hsa-miR-433-3p YES NO YES hsa-miR-451a YES YES YES hsa-miR-488-3p YES YES NO hsa-miR-496 YES YES NO hsa-miR-520a-3p YES YES YES hsa-miR-520b YES YES YES hsa-miR-520c-3p YES YES YES hsa-miR-520d-3p YES YES YES hsa-miR-520e YES YES YES hsa-miR-582-5p YES NO YES hsa-miR-599 YES YES NO hsa-miR-613 YES YES YES hsa-miR-655-3p YES NO YES hsa-miR-708-5p YES YES YES hsa-miR-760 YES NO YES hsa-miR-876-5p YES YES YES hsa-miR-92a-3p NO YES YES hsa-miR-92b-3p NO YES YES Display: