Entry Detail



General Information

Database ID:BRCA01092
Cancer Type:breast cancer
Dataset:GSE109761
CTCs/CTM Isolation Method:microfluidics immunofluorescence



Gene Information

ncRNA Symbol:PFN1
Full Name:profilin 1
Category:mRNA
Synonyms:ALS18
Chromosome:chr17
Strand:-
Coordinate:
Start Site(bp):4945652End Site(bp):4949061
Gene Summary:This gene encodes a member of the profilin family of small actin-binding proteins. The encoded protein plays an important role in actin dynamics by regulating actin polymerization in response to extracellular signals. Deletion of this gene is associated with Miller-Dieker syndrome, and the encoded protein may also play a role in Huntington disease. Multiple pseudogenes of this gene are located on chromosome 1. [provided by RefSeq, Jul 2012]
External Links:
Ensembl ID:ENSG00000108518
HGNC ID:HGNC:8881
Entrez Gene:5216



Expression Profile of PFN1 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-1271-5p
YES
NO
YES
hsa-miR-182-5p
YES
NO
YES
hsa-miR-19a-3p
YES
YES
YES
hsa-miR-19b-3p
YES
YES
YES
hsa-miR-320a
YES
YES
NO
hsa-miR-320b
YES
YES
NO
hsa-miR-320c
YES
YES
NO
hsa-miR-320d
YES
YES
NO
hsa-miR-328-3p
YES
YES
NO
hsa-miR-411-5p
YES
YES
NO
hsa-miR-491-5p
YES
YES
NO
hsa-miR-599
YES
YES
NO
hsa-miR-96-5p
YES
NO
YES
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