ctcRbase

Entry Detail

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General Information

Database ID: BRCA01093 Cancer Type: breast cancer Dataset: GSE41245 CTCs/CTM Isolation Method: CTC-Chip

Gene Information

ncRNA Symbol: HNRNPL Full Name: heterogeneous nuclear ribonucleoprotein L Category: mRNA Synonyms: HNRPL|P/OKcl.14|hnRNP-L Chromosome: chr19 Strand: - Coordinate: Start Site(bp): 38836388 End Site(bp): 38852347 Gene Summary: Heterogeneous nuclear RNAs (hnRNAs) which include mRNA precursors and mature mRNAs are associated with specific proteins to form heterogenous ribonucleoprotein (hnRNP) complexes. Heterogeneous nuclear ribonucleoprotein L is among the proteins that are stably associated with hnRNP complexes and along with other hnRNP proteins is likely to play a major role in the formation, packaging, processing, and function of mRNA. Heterogeneous nuclear ribonucleoprotein L is present in the nucleoplasm as part of the HNRP complex. HNRP proteins have also been identified outside of the nucleoplasm. Exchange of hnRNP for mRNA-binding proteins accompanies transport of mRNA from the nucleus to the cytoplasm. Since HNRP proteins have been shown to shuttle between the nucleus and the cytoplasm, it is possible that they also have cytoplasmic functions. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000104824 HGNC ID: HGNC:5045 Entrez Gene: 3191

Expression Profile of HNRNPL Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-103a-3p YES YES NO hsa-miR-106a-5p YES YES NO hsa-miR-106b-5p YES YES NO hsa-miR-107 YES YES NO hsa-miR-17-5p YES YES NO hsa-miR-20a-5p YES YES NO hsa-miR-20b-5p YES YES NO hsa-miR-212-3p YES YES NO hsa-miR-23a-3p YES YES NO hsa-miR-23b-3p YES YES NO hsa-miR-300 YES YES YES hsa-miR-335-5p YES YES NO hsa-miR-370-3p YES NO YES hsa-miR-381-3p YES YES YES hsa-miR-455-5p YES YES YES hsa-miR-493-3p YES NO YES hsa-miR-519d-3p YES YES NO hsa-miR-873-5p YES YES NO hsa-miR-93-5p YES YES NO Display: