Entry Detail



General Information

Database ID:BRCA01131
Cancer Type:breast cancer
Dataset:GSE109761
CTCs/CTM Isolation Method:microfluidics immunofluorescence



Gene Information

ncRNA Symbol:HNRNPC
Full Name:heterogeneous nuclear ribonucleoprotein C (C1/C2)
Category:mRNA
Synonyms:C1|C2|HNRNP|HNRPC|SNRPC
Chromosome:chr14
Strand:-
Coordinate:
Start Site(bp):21209136End Site(bp):21269494
Gene Summary:This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene can act as a tetramer and is involved in the assembly of 40S hnRNP particles. Multiple transcript variants encoding at least two different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
External Links:
Ensembl ID:ENSG00000092199
HGNC ID:HGNC:5035
Entrez Gene:3183



Expression Profile of HNRNPC Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-let-7a-5p
YES
YES
NO
hsa-let-7b-5p
YES
YES
NO
hsa-let-7c-5p
YES
YES
NO
hsa-let-7d-5p
YES
YES
NO
hsa-let-7e-5p
YES
YES
NO
hsa-let-7f-5p
YES
YES
NO
hsa-let-7g-5p
YES
YES
NO
hsa-let-7i-5p
YES
YES
NO
hsa-miR-128-3p
YES
YES
NO
hsa-miR-141-3p
YES
YES
NO
hsa-miR-142-3p
YES
YES
YES
hsa-miR-143-3p
YES
YES
NO
hsa-miR-144-3p
YES
YES
YES
hsa-miR-145-5p
YES
YES
NO
hsa-miR-153-3p
YES
YES
NO
hsa-miR-185-5p
YES
YES
NO
hsa-miR-186-5p
YES
YES
YES
hsa-miR-200a-3p
YES
YES
NO
hsa-miR-208a-3p
YES
YES
NO
hsa-miR-208b-3p
YES
YES
NO
hsa-miR-218-5p
NO
YES
YES
hsa-miR-224-5p
YES
YES
YES
hsa-miR-28-5p
YES
YES
YES
hsa-miR-299-5p
YES
NO
YES
hsa-miR-300
YES
YES
NO
hsa-miR-30a-5p
YES
YES
YES
hsa-miR-30b-5p
YES
YES
YES
hsa-miR-30c-5p
YES
YES
YES
hsa-miR-30d-5p
YES
YES
YES
hsa-miR-30e-5p
YES
YES
YES
hsa-miR-320a
YES
YES
YES
hsa-miR-320b
YES
YES
YES
hsa-miR-320c
YES
YES
YES
hsa-miR-320d
YES
YES
YES
hsa-miR-330-3p
YES
NO
YES
hsa-miR-335-5p
YES
YES
NO
hsa-miR-361-5p
YES
YES
NO
hsa-miR-381-3p
YES
YES
NO
hsa-miR-411-5p
YES
YES
NO
hsa-miR-433-3p
YES
YES
NO
hsa-miR-455-5p
NO
YES
YES
hsa-miR-489-3p
YES
NO
YES
hsa-miR-495-3p
YES
YES
NO
hsa-miR-499a-5p
YES
YES
YES
hsa-miR-543
YES
YES
NO
hsa-miR-653-5p
YES
YES
NO
hsa-miR-708-5p
YES
YES
YES
hsa-miR-873-5p
YES
YES
NO
hsa-miR-877-5p
YES
NO
YES
hsa-miR-98-5p
YES
YES
NO
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