Entry Detail



General Information

Database ID:BRCA01157
Cancer Type:breast cancer
Dataset:GSE111065
CTCs/CTM Isolation Method:microfluidics immunofluorescence



Gene Information

ncRNA Symbol:JUP
Full Name:junction plakoglobin
Category:mRNA
Synonyms:CTNNG|DP3|DPIII|PDGB|PKGB
Chromosome:chr17
Strand:-
Coordinate:
Start Site(bp):41754604End Site(bp):41786931
Gene Summary:This gene encodes a major cytoplasmic protein which is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins and is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat. Mutation in this gene has been associated with Naxos disease. Alternative splicing occurs in this gene; however, not all transcripts have been fully described. [provided by RefSeq, Jul 2008]
External Links:
Ensembl ID:ENSG00000173801
HGNC ID:HGNC:6207
Entrez Gene:3728



Expression Profile of JUP Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-15a-5p
YES
YES
NO
hsa-miR-15b-5p
YES
YES
NO
hsa-miR-16-5p
YES
YES
NO
hsa-miR-185-5p
YES
YES
NO
hsa-miR-195-5p
YES
YES
NO
hsa-miR-197-3p
YES
YES
NO
hsa-miR-214-3p
YES
YES
NO
hsa-miR-324-5p
YES
YES
NO
hsa-miR-329-3p
YES
YES
NO
hsa-miR-335-5p
YES
YES
YES
hsa-miR-362-3p
YES
YES
NO
hsa-miR-424-5p
YES
YES
NO
hsa-miR-431-5p
YES
YES
NO
hsa-miR-497-5p
YES
YES
NO
Display: