ctcRbase

Entry Detail

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General Information

Database ID: BRCA01206 Cancer Type: breast cancer Dataset: GSE41245 CTCs/CTM Isolation Method: CTC-Chip

Gene Information

ncRNA Symbol: MAFF Full Name: MAF bZIP transcription factor F Category: mRNA Synonyms: U-MAF|hMafF Chromosome: chr22 Strand: + Coordinate: Start Site(bp): 38200767 End Site(bp): 38216511 Gene Summary: The protein encoded by this gene is a basic leucine zipper (bZIP) transcription factor that lacks a transactivation domain. It is known to bind the US-2 DNA element in the promoter of the oxytocin receptor (OTR) gene and most likely heterodimerizes with other leucine zipper-containing proteins to enhance expression of the OTR gene during term pregnancy. The encoded protein can also form homodimers, and since it lacks a transactivation domain, the homodimer may act as a repressor of transcription. This gene may also be involved in the cellular stress response. Multiple transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2009] External Links: Ensembl ID: ENSG00000185022 HGNC ID: HGNC:6780 Entrez Gene: 23764

Expression Profile of MAFF Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-1271-5p YES YES NO hsa-miR-130a-3p YES YES NO hsa-miR-130b-3p YES YES NO hsa-miR-133a-3p YES YES NO hsa-miR-133b YES YES NO hsa-miR-148a-3p YES YES NO hsa-miR-148b-3p YES YES NO hsa-miR-152-3p YES YES NO hsa-miR-214-3p YES YES NO hsa-miR-224-5p YES YES NO hsa-miR-301a-3p YES YES NO hsa-miR-301b-3p YES YES NO hsa-miR-454-3p YES YES NO hsa-miR-7-5p YES YES NO hsa-miR-760 YES NO YES hsa-miR-96-5p YES YES NO Display: