ctcRbase

Entry Detail

---



General Information

Database ID: BRCA01212 Cancer Type: breast cancer Dataset: GSE109761 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: COX5A Full Name: cytochrome c oxidase subunit 5A Category: mRNA Synonyms: COX|COX-VA|VA Chromosome: chr15 Strand: - Coordinate: Start Site(bp): 74919791 End Site(bp): 74938168 Gene Summary: Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer of proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit Va of the human mitochondrial respiratory chain enzyme. A pseudogene COX5AP1 has been found in chromosome 14q22. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000178741 HGNC ID: HGNC:2267 Entrez Gene: 9377

Expression Profile of COX5A Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-1297 YES YES YES hsa-miR-135a-5p YES YES NO hsa-miR-135b-5p YES YES NO hsa-miR-204-5p YES YES YES hsa-miR-211-5p YES YES YES hsa-miR-26a-5p YES YES YES hsa-miR-26b-5p YES YES YES hsa-miR-362-5p YES NO YES hsa-miR-375 YES YES NO hsa-miR-377-3p YES YES NO Display: