Entry Detail



General Information

Database ID:BRCA01252
Cancer Type:breast cancer
Dataset:GSE55807
CTCs/CTM Isolation Method:CTC-iChip



Gene Information

ncRNA Symbol:MDH2
Full Name:malate dehydrogenase 2
Category:mRNA
Synonyms:EIEE51|M-MDH|MDH|MGC:3559|MOR1
Chromosome:chr7
Strand:+
Coordinate:
Start Site(bp):76048051End Site(bp):76067508
Gene Summary:Malate dehydrogenase catalyzes the reversible oxidation of malate to oxaloacetate, utilizing the NAD/NADH cofactor system in the citric acid cycle. The protein encoded by this gene is localized to the mitochondria and may play pivotal roles in the malate-aspartate shuttle that operates in the metabolic coordination between cytosol and mitochondria. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013]
External Links:
Ensembl ID:ENSG00000146701
HGNC ID:HGNC:6971
Entrez Gene:4191



Expression Profile of MDH2 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-144-3p
YES
YES
NO
hsa-miR-193a-3p
YES
YES
NO
hsa-miR-193b-3p
YES
YES
NO
hsa-miR-205-5p
YES
YES
NO
hsa-miR-532-5p
YES
NO
YES
Display: