Entry Detail



General Information

Database ID:BRCA01294
Cancer Type:breast cancer
Dataset:GSE55807
CTCs/CTM Isolation Method:CTC-iChip



Gene Information

ncRNA Symbol:PEBP1
Full Name:phosphatidylethanolamine binding protein 1
Category:mRNA
Synonyms:HCNP|HCNPpp|HEL-210|HEL-S-34|HEL-S-96|PBP|PEBP|PEBP-1|RKIP
Chromosome:chr12
Strand:+
Coordinate:
Start Site(bp):118135858End Site(bp):118145584
Gene Summary:This gene encodes a member of the phosphatidylethanolamine-binding family of proteins and has been shown to modulate multiple signaling pathways, including the MAP kinase (MAPK), NF-kappa B, and glycogen synthase kinase-3 (GSK-3) signaling pathways. The encoded protein can be further processed to form a smaller cleavage product, hippocampal cholinergic neurostimulating peptide (HCNP), which may be involved in neural development. This gene has been implicated in numerous human cancers and may act as a metastasis suppressor gene. Multiple pseudogenes of this gene have been identified in the genome. [provided by RefSeq, Jul 2015]
External Links:
Ensembl ID:ENSG00000089220
HGNC ID:HGNC:8630
Entrez Gene:5037



Expression Profile of PEBP1 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-101-3p
YES
YES
NO
hsa-miR-141-3p
YES
YES
NO
hsa-miR-181a-5p
YES
YES
NO
hsa-miR-181b-5p
YES
YES
NO
hsa-miR-181c-5p
YES
YES
NO
hsa-miR-181d-5p
YES
YES
NO
hsa-miR-200a-3p
YES
YES
NO
hsa-miR-214-3p
YES
YES
NO
hsa-miR-224-5p
YES
YES
YES
hsa-miR-23a-3p
YES
YES
NO
hsa-miR-23b-3p
YES
YES
NO
hsa-miR-27a-3p
YES
YES
NO
hsa-miR-27b-3p
YES
YES
NO
hsa-miR-340-5p
YES
YES
NO
hsa-miR-378a-3p
YES
YES
NO
hsa-miR-422a
YES
YES
NO
hsa-miR-543
YES
YES
NO
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