ctcRbase

Entry Detail

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General Information

Database ID: BRCA01297 Cancer Type: breast cancer Dataset: GSE55807 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: PSMA3 Full Name: proteasome subunit alpha 3 Category: mRNA Synonyms: HC8|PSC3 Chromosome: chr14 Strand: + Coordinate: Start Site(bp): 58244831 End Site(bp): 58272012 Gene Summary: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Two alternative transcripts encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000100567 HGNC ID: HGNC:9532 Entrez Gene: 5684

Expression Profile of PSMA3 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-144-3p YES YES NO hsa-miR-208a-3p YES YES NO hsa-miR-208b-3p YES YES NO hsa-miR-300 YES YES NO hsa-miR-381-3p YES YES NO hsa-miR-411-5p YES YES NO hsa-miR-499a-5p YES YES NO Display: