ncRNA Symbol: | TMED10 |
Full Name: | transmembrane p24 trafficking protein 10 |
Category: | mRNA |
Synonyms: | P24(DELTA)|S31I125|S31III125|TMP21|Tmp-21-I|p23|p24d1 |
Chromosome: | chr14 |
Strand: | - |
Coordinate: | Start Site(bp): | 75131470 | End Site(bp): | 75176631 | |
Gene Summary: | This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8. [provided by RefSeq, Jul 2008] |
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