ctcRbase

Entry Detail

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General Information

Database ID: BRCA01325 Cancer Type: breast cancer Dataset: GSE41245 CTCs/CTM Isolation Method: CTC-Chip

Gene Information

ncRNA Symbol: VAMP2 Full Name: vesicle associated membrane protein 2 Category: mRNA Synonyms: SYB2|VAMP-2 Chromosome: chr17 Strand: - Coordinate: Start Site(bp): 8159149 End Site(bp): 8163546 Gene Summary: The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. This gene is thought to participate in neurotransmitter release at a step between docking and fusion. The protein forms a stable complex with syntaxin, synaptosomal-associated protein, 25 kD, and synaptotagmin. It also forms a distinct complex with synaptophysin. It is a likely candidate gene for familial infantile myasthenia (FIMG) because of its map location and because it encodes a synaptic vesicle protein of the type that has been implicated in the pathogenesis of FIMG. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000220205 HGNC ID: HGNC:12643 Entrez Gene: 6844

Expression Profile of VAMP2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-127-3p YES YES NO hsa-miR-133a-3p YES YES YES hsa-miR-133b YES YES YES hsa-miR-135a-5p YES NO YES hsa-miR-135b-5p YES NO YES hsa-miR-1-3p YES YES YES hsa-miR-149-5p YES YES NO hsa-miR-150-5p YES YES NO hsa-miR-19a-3p YES YES NO hsa-miR-19b-3p YES YES NO hsa-miR-206 YES YES YES hsa-miR-223-3p YES YES YES hsa-miR-28-5p YES NO YES hsa-miR-300 YES YES NO hsa-miR-31-5p YES YES NO hsa-miR-324-5p YES YES NO hsa-miR-326 YES YES YES hsa-miR-329-3p YES NO NO hsa-miR-330-5p YES YES YES hsa-miR-338-3p YES YES NO hsa-miR-340-5p YES YES NO hsa-miR-34a-5p YES YES YES hsa-miR-34c-5p YES YES YES hsa-miR-362-3p YES NO NO hsa-miR-369-3p YES NO YES hsa-miR-374a-5p YES YES YES hsa-miR-374b-5p YES YES YES hsa-miR-378a-3p YES YES NO hsa-miR-381-3p YES YES NO hsa-miR-410-3p YES YES YES hsa-miR-422a YES YES NO hsa-miR-449a YES YES YES hsa-miR-449b-5p YES YES YES hsa-miR-455-3p YES NO YES hsa-miR-613 YES YES YES hsa-miR-708-5p YES NO YES Display: