Entry Detail



General Information

Database ID:BRCA01340
Cancer Type:breast cancer
Dataset:GSE41245
CTCs/CTM Isolation Method:CTC-Chip



Gene Information

ncRNA Symbol:FGF18
Full Name:fibroblast growth factor 18
Category:mRNA
Synonyms:FGF-18|ZFGF5
Chromosome:chr5
Strand:+
Coordinate:
Start Site(bp):171419656End Site(bp):171457623
Gene Summary:The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. It has been shown in vitro that this protein is able to induce neurite outgrowth in PC12 cells. Studies of the similar proteins in mouse and chick suggested that this protein is a pleiotropic growth factor that stimulates proliferation in a number of tissues, most notably the liver and small intestine. Knockout studies of the similar gene in mice implied the role of this protein in regulating proliferation and differentiation of midline cerebellar structures. [provided by RefSeq, Jul 2008]
External Links:
Ensembl ID:ENSG00000156427
HGNC ID:HGNC:3674
Entrez Gene:8817



Expression Profile of FGF18 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-326
YES
YES
NO
hsa-miR-330-5p
YES
YES
NO
hsa-miR-371a-5p
YES
YES
NO
hsa-miR-9-5p
YES
YES
YES
Display: