Entry Detail



General Information

Database ID:BRCA01407
Cancer Type:breast cancer
Dataset:GSE109761
CTCs/CTM Isolation Method:microfluidics immunofluorescence



Gene Information

ncRNA Symbol:CD44
Full Name:CD44 molecule (Indian blood group)
Category:mRNA
Synonyms:CDW44|CSPG8|ECMR-III|HCELL|HUTCH-I|IN|LHR|MC56|MDU2|MDU3|MIC4|Pgp1
Chromosome:chr11
Strand:+
Coordinate:
Start Site(bp):35138870End Site(bp):35232402
Gene Summary:The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis. [provided by RefSeq, Jul 2008]
External Links:
Ensembl ID:ENSG00000026508
HGNC ID:HGNC:1681
Entrez Gene:960



Expression Profile of CD44 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-124-3p
YES
YES
NO
hsa-miR-132-3p
YES
YES
NO
hsa-miR-143-3p
YES
YES
NO
hsa-miR-144-3p
YES
YES
NO
hsa-miR-185-5p
YES
YES
NO
hsa-miR-199a-3p
YES
NO
YES
hsa-miR-199b-3p
YES
NO
YES
hsa-miR-204-5p
YES
YES
NO
hsa-miR-211-5p
YES
YES
NO
hsa-miR-216b-5p
YES
YES
NO
hsa-miR-302a-3p
YES
YES
NO
hsa-miR-302b-3p
YES
YES
NO
hsa-miR-302c-3p
YES
YES
NO
hsa-miR-302d-3p
YES
YES
NO
hsa-miR-302e
YES
YES
NO
hsa-miR-340-5p
YES
YES
NO
hsa-miR-372-3p
YES
YES
NO
hsa-miR-373-3p
YES
YES
NO
hsa-miR-410-3p
YES
YES
NO
hsa-miR-485-5p
YES
YES
NO
hsa-miR-506-3p
YES
YES
NO
hsa-miR-520a-3p
YES
YES
NO
hsa-miR-520b
YES
YES
NO
hsa-miR-520c-3p
YES
YES
NO
hsa-miR-520d-3p
YES
YES
NO
hsa-miR-520e
YES
YES
NO
hsa-miR-625-5p
YES
NO
NO
hsa-miR-653-5p
YES
YES
NO
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