ctcRbase

Entry Detail

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General Information

Database ID: BRCA12586 Cancer Type: breast cancer Dataset: GSE41245 CTCs/CTM Isolation Method: CTC-Chip

Gene Information

ncRNA Symbol: PANK1 Full Name: pantothenate kinase 1 Category: mRNA Synonyms: PANK Chromosome: chr10 Strand: - Coordinate: Start Site(bp): 89579497 End Site(bp): 89645572 Gene Summary: This gene encodes a member of the pantothenate kinase family. Pantothenate kinases are key regulatory enzymes in the biosynthesis of coenzyme A (CoA). The encoded protein catalyzes the first and rate-limiting enzymatic reaction in CoA biosynthesis and is regulated by CoA through feedback inhibition. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. This gene and an intronic miRNA on the same strand are co-regulated by the tumor suppressor p53 (see PMID 20833636). [provided by RefSeq, Apr 2011] External Links: Ensembl ID: ENSG00000152782 HGNC ID: HGNC:8598 Entrez Gene: 53354

Expression Profile of PANK1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-101-3p YES YES YES hsa-miR-103a-3p YES YES NO hsa-miR-107 YES YES NO hsa-miR-1224-5p YES NO YES hsa-miR-128-3p YES YES YES hsa-miR-135a-5p YES YES YES hsa-miR-135b-5p YES YES YES hsa-miR-144-3p YES YES YES hsa-miR-153-3p YES YES NO hsa-miR-155-5p YES YES YES hsa-miR-15a-5p YES YES YES hsa-miR-15b-5p YES YES YES hsa-miR-16-5p YES YES YES hsa-miR-181a-5p YES YES NO hsa-miR-181b-5p YES YES NO hsa-miR-181c-5p YES YES NO hsa-miR-181d-5p YES YES NO hsa-miR-195-5p YES YES YES hsa-miR-197-3p YES YES NO hsa-miR-204-5p YES YES NO hsa-miR-205-5p YES YES NO hsa-miR-211-5p YES YES NO hsa-miR-214-3p YES YES NO hsa-miR-216a-5p YES YES NO hsa-miR-216b-5p YES YES NO hsa-miR-218-5p YES YES NO hsa-miR-224-5p YES YES NO hsa-miR-27a-3p YES YES YES hsa-miR-27b-3p YES YES YES hsa-miR-335-5p YES YES NO hsa-miR-338-3p YES NO YES hsa-miR-340-5p YES YES NO hsa-miR-383-5p YES NO YES hsa-miR-384 YES YES NO hsa-miR-410-3p YES YES NO hsa-miR-424-5p YES YES YES hsa-miR-433-3p YES YES NO hsa-miR-448 YES YES NO hsa-miR-485-5p YES YES NO hsa-miR-495-3p YES YES NO hsa-miR-497-5p YES YES YES hsa-miR-543 YES YES NO hsa-miR-876-5p YES YES NO Display: