ctcRbase

Entry Detail

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General Information

Database ID: BRCA12794 Cancer Type: breast cancer Dataset: GSE41245 CTCs/CTM Isolation Method: CTC-Chip

Gene Information

ncRNA Symbol: HOXC6 Full Name: homeobox C6 Category: mRNA Synonyms: CP25|HHO.C8|HOX3|HOX3C Chromosome: chr12 Strand: + Coordinate: Start Site(bp): 53990624 End Site(bp): 54030823 Gene Summary: This gene belongs to the homeobox family, members of which encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene, HOXC6, is one of several HOXC genes located in a cluster on chromosome 12. Three genes, HOXC5, HOXC4 and HOXC6, share a 5' non-coding exon. Transcripts may include the shared exon spliced to the gene-specific exons, or they may include only the gene-specific exons. Alternatively spliced transcript variants encoding different isoforms have been identified for HOXC6. Transcript variant two includes the shared exon, and transcript variant one includes only gene-specific exons. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000197757 HGNC ID: HGNC:5128 Entrez Gene: 3223

Expression Profile of HOXC6 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-128-3p YES NO YES hsa-miR-129-5p YES YES NO hsa-miR-141-3p YES YES NO hsa-miR-146a-5p YES YES NO hsa-miR-146b-5p YES YES NO hsa-miR-149-5p YES YES NO hsa-miR-193a-3p YES YES NO hsa-miR-193b-3p YES YES NO hsa-miR-199a-5p YES YES NO hsa-miR-199b-5p YES YES NO hsa-miR-200a-3p YES YES NO hsa-miR-210-3p YES YES NO hsa-miR-27a-3p YES YES YES hsa-miR-27b-3p YES YES YES hsa-miR-340-5p YES YES NO hsa-miR-361-5p YES YES NO hsa-miR-377-3p YES YES YES hsa-miR-410-3p YES YES NO hsa-miR-495-3p YES YES NO hsa-miR-615-3p YES YES NO hsa-miR-876-5p YES YES NO Display: