ctcRbase

Entry Detail

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General Information

Database ID: BRCA13181 Cancer Type: breast cancer Dataset: GSE55807 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: MARCKS Full Name: myristoylated alanine rich protein kinase C substrate Category: mRNA Synonyms: 80K-L|MACS|PKCSL|PRKCSL Chromosome: chr6 Strand: + Coordinate: Start Site(bp): 113857362 End Site(bp): 113863471 Gene Summary: The protein encoded by this gene is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000277443 HGNC ID: HGNC:6759 Entrez Gene: 4082

Expression Profile of MARCKS Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-10a-5p YES YES NO hsa-miR-10b-5p YES YES NO hsa-miR-128-3p YES YES NO hsa-miR-135a-5p YES YES NO hsa-miR-135b-5p YES YES NO hsa-miR-138-5p YES YES YES hsa-miR-1-3p YES NO YES hsa-miR-140-3p YES NO YES hsa-miR-142-3p YES YES YES hsa-miR-143-3p YES NO YES hsa-miR-144-3p YES NO YES hsa-miR-145-5p YES YES NO hsa-miR-181a-5p YES YES YES hsa-miR-181b-5p YES YES YES hsa-miR-181c-5p YES YES YES hsa-miR-181d-5p YES YES YES hsa-miR-182-5p YES YES NO hsa-miR-188-5p YES NO YES hsa-miR-200b-3p YES YES YES hsa-miR-200c-3p YES YES YES hsa-miR-204-5p YES YES YES hsa-miR-205-5p YES YES YES hsa-miR-206 YES NO YES hsa-miR-211-5p YES YES YES hsa-miR-218-5p YES YES NO hsa-miR-221-3p YES YES YES hsa-miR-222-3p YES YES YES hsa-miR-224-5p YES YES YES hsa-miR-23a-3p YES YES NO hsa-miR-23b-3p YES YES NO hsa-miR-27a-3p YES YES YES hsa-miR-27b-3p YES YES YES hsa-miR-299-5p YES NO YES hsa-miR-300 YES YES YES hsa-miR-30a-5p YES NO YES hsa-miR-30b-5p YES NO YES hsa-miR-30c-5p YES NO YES hsa-miR-30d-5p YES NO YES hsa-miR-30e-5p YES NO YES hsa-miR-338-3p YES YES NO hsa-miR-342-3p YES YES NO hsa-miR-34a-5p YES YES NO hsa-miR-34c-5p YES YES NO hsa-miR-370-3p YES YES YES hsa-miR-371a-5p YES YES YES hsa-miR-381-3p YES YES YES hsa-miR-410-3p YES YES NO hsa-miR-429 YES YES YES hsa-miR-449a YES YES NO hsa-miR-449b-5p YES YES NO hsa-miR-491-5p YES YES YES hsa-miR-495-3p YES YES YES hsa-miR-499a-5p YES YES YES hsa-miR-501-3p YES NO YES hsa-miR-502-3p YES NO YES hsa-miR-5688 NO NO YES hsa-miR-599 YES YES NO hsa-miR-613 YES NO YES hsa-miR-655-3p YES NO YES hsa-miR-802 YES NO YES Display: