ctcRbase

Entry Detail

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General Information

Database ID: BRCA15551 Cancer Type: breast cancer Dataset: GSE75367 CTCs/CTM Isolation Method: micromanipulation immunofluorescence

Gene Information

ncRNA Symbol: PIK3R1 Full Name: phosphoinositide-3-kinase regulatory subunit 1 Category: mRNA Synonyms: AGM7|GRB1|IMD36|p85|p85-ALPHA Chromosome: chr5 Strand: + Coordinate: Start Site(bp): 68215720 End Site(bp): 68301821 Gene Summary: Phosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. This gene encodes the 85 kD regulatory subunit. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance. Alternative splicing of this gene results in four transcript variants encoding different isoforms. [provided by RefSeq, Jun 2011] External Links: Ensembl ID: ENSG00000145675 HGNC ID: HGNC:8979 Entrez Gene: 5295

Expression Profile of PIK3R1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-103a-3p YES YES YES hsa-miR-106a-5p YES NO YES hsa-miR-106b-5p YES NO YES hsa-miR-107 YES YES YES hsa-miR-1271-5p YES NO YES hsa-miR-128-3p YES NO YES hsa-miR-129-5p YES YES NO hsa-miR-1323 YES NO NO hsa-miR-132-3p YES YES NO hsa-miR-136-5p YES YES NO hsa-miR-150-5p YES YES NO hsa-miR-153-3p YES YES YES hsa-miR-155-5p YES YES YES hsa-miR-15a-5p YES YES YES hsa-miR-15b-5p YES YES YES hsa-miR-16-5p YES YES YES hsa-miR-17-5p YES NO YES hsa-miR-182-5p YES NO YES hsa-miR-194-5p YES YES NO hsa-miR-195-5p YES YES YES hsa-miR-199a-5p YES YES NO hsa-miR-199b-5p YES YES NO hsa-miR-20a-5p YES NO YES hsa-miR-20b-5p YES NO YES hsa-miR-212-3p YES YES NO hsa-miR-21-5p YES YES YES hsa-miR-216a-5p YES YES NO hsa-miR-221-3p YES YES YES hsa-miR-222-3p YES YES YES hsa-miR-25-3p YES YES NO hsa-miR-29a-3p YES YES YES hsa-miR-29b-3p YES YES YES hsa-miR-29c-3p YES YES YES hsa-miR-320a YES NO YES hsa-miR-320b YES NO YES hsa-miR-320c YES NO YES hsa-miR-320d YES NO YES hsa-miR-32-5p YES YES NO hsa-miR-329-3p YES NO NO hsa-miR-361-5p YES YES NO hsa-miR-362-3p YES NO NO hsa-miR-363-3p YES YES NO hsa-miR-367-3p YES YES NO hsa-miR-376a-3p YES YES YES hsa-miR-376b-3p YES YES YES hsa-miR-424-5p YES YES YES hsa-miR-431-5p YES YES NO hsa-miR-448 YES YES NO hsa-miR-455-3p YES NO YES hsa-miR-486-5p YES YES YES hsa-miR-488-3p YES YES YES hsa-miR-491-5p YES YES NO hsa-miR-496 YES YES NO hsa-miR-497-5p YES YES YES hsa-miR-503-5p YES NO YES hsa-miR-519d-3p YES NO YES hsa-miR-542-3p YES YES NO hsa-miR-548o-3p YES NO NO hsa-miR-590-5p YES YES YES hsa-miR-655-3p YES NO YES hsa-miR-876-5p YES YES NO hsa-miR-92a-3p YES YES NO hsa-miR-92b-3p YES YES NO hsa-miR-93-5p YES NO YES hsa-miR-96-5p YES NO YES Display: