ctcRbase

Entry Detail

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General Information

Database ID: BRCA22752 Cancer Type: breast cancer Dataset: GSE41245 CTCs/CTM Isolation Method: CTC-Chip

Gene Information

ncRNA Symbol: SENP3 Full Name: SUMO specific peptidase 3 Category: mRNA Synonyms: SMT3IP1|SSP3|Ulp1 Chromosome: chr17 Strand: + Coordinate: Start Site(bp): 7561875 End Site(bp): 7571969 Gene Summary: The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1; MIM 601912) is required for numerous biologic processes. SUMO-specific proteases, such as SENP3, are responsible for the initial processing of SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also have isopeptidase activity for the removal of SUMO from high molecular mass SUMO conjugates (Di Bacco et al., 2006 [PubMed 16738315]).[supplied by OMIM, Jun 2009] External Links: Ensembl ID: ENSG00000161956 HGNC ID: HGNC:17862 Entrez Gene: 26168

Expression Profile of SENP3 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-31-5p YES YES NO hsa-miR-34a-5p YES YES NO hsa-miR-34c-5p YES YES NO hsa-miR-371a-5p YES YES NO hsa-miR-449a YES YES NO hsa-miR-449b-5p YES YES NO hsa-miR-494-3p YES YES NO hsa-miR-543 YES YES NO Display: