ctcRbase

Entry Detail

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General Information

Database ID: BRCA23616 Cancer Type: breast cancer Dataset: GSE111065 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: PTGES Full Name: prostaglandin E synthase Category: mRNA Synonyms: MGST-IV|MGST1-L1|MGST1L1|MPGES|PGES|PIG12|PP102|PP1294|TP53I12|mPGES-1 Chromosome: chr9 Strand: - Coordinate: Start Site(bp): 129738331 End Site(bp): 129753047 Gene Summary: The protein encoded by this gene is a glutathione-dependent prostaglandin E synthase. The expression of this gene has been shown to be induced by proinflammatory cytokine interleukin 1 beta (IL1B). Its expression can also be induced by tumor suppressor protein TP53, and may be involved in TP53 induced apoptosis. Knockout studies in mice suggest that this gene may contribute to the pathogenesis of collagen-induced arthritis and mediate acute pain during inflammatory responses. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000148344 HGNC ID: HGNC:9599 Entrez Gene: 9536

Expression Profile of PTGES Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-122-5p YES YES NO hsa-miR-1321 YES NO NO hsa-miR-329-3p YES NO NO hsa-miR-362-3p YES NO NO hsa-miR-377-3p YES YES NO hsa-miR-494-3p YES YES NO Display: