Entry Detail



General Information

Database ID:BRCA23692
Cancer Type:breast cancer
Dataset:GSE109761
CTCs/CTM Isolation Method:microfluidics immunofluorescence



Gene Information

ncRNA Symbol:TPBG
Full Name:trophoblast glycoprotein
Category:mRNA
Synonyms:5T4|5T4AG|M6P1|WAIF1
Chromosome:chr6
Strand:+
Coordinate:
Start Site(bp):82363206End Site(bp):82370828
Gene Summary:This gene encodes a leucine-rich transmembrane glycoprotein that may be involved in cell adhesion. The encoded protein is an oncofetal antigen that is specific to trophoblast cells. In adults this protein is highly expressed in many tumor cells and is associated with poor clinical outcome in numerous cancers. Alternate splicing in the 5' UTR results in multiple transcript variants that encode the same protein. [provided by RefSeq, Oct 2009]
External Links:
Ensembl ID:ENSG00000146242
HGNC ID:HGNC:12004
Entrez Gene:7162



Expression Profile of TPBG Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-129-5p
YES
YES
NO
hsa-miR-132-3p
YES
YES
NO
hsa-miR-186-5p
YES
YES
NO
hsa-miR-212-3p
YES
YES
NO
hsa-miR-217
YES
YES
NO
hsa-miR-329-3p
YES
YES
NO
hsa-miR-340-5p
YES
YES
NO
hsa-miR-362-3p
YES
YES
NO
hsa-miR-410-3p
YES
YES
NO
hsa-miR-653-5p
YES
YES
NO
Display: