| ncRNA Symbol: | ALOX15B | | Full Name: | arachidonate 15-lipoxygenase, type B | | Category: | mRNA | | Synonyms: | 15-LOX-2 | | Chromosome: | chr17 | | Strand: | + | | Coordinate: | | Start Site(bp): | 8039017 | End Site(bp): | 8049134 |
| | Gene Summary: | This gene encodes a member of the lipoxygenase family of structurally related nonheme iron dioxygenases involved in the production of fatty acid hydroperoxides. The encoded protein converts arachidonic acid exclusively to 15S-hydroperoxyeicosatetraenoic acid, while metabolizing linoleic acid less effectively. This gene is located in a cluster of related genes and a pseudogene that spans approximately 100 kilobases on the short arm of chromosome 17. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008] | | External Links: | |
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