ctcRbase

Entry Detail

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General Information

Database ID: BRCA24705 Cancer Type: breast cancer Dataset: GSE109761 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: EIF4G3 Full Name: eukaryotic translation initiation factor 4 gamma 3 Category: mRNA Synonyms: eIF-4G 3|eIF4G 3|eIF4GII Chromosome: chr1 Strand: - Coordinate: Start Site(bp): 20806292 End Site(bp): 21176888 Gene Summary: The protein encoded by this gene is thought to be part of the eIF4F protein complex, which is involved in mRNA cap recognition and transport of mRNAs to the ribosome. Interestingly, a microRNA (miR-520c-3p) has been found that negatively regulates synthesis of the encoded protein, and this leads to a global decrease in protein translation and cell proliferation. Therefore, this protein is a key component of the anti-tumor activity of miR-520c-3p. [provided by RefSeq, May 2016] External Links: Ensembl ID: ENSG00000075151 HGNC ID: HGNC:3298 Entrez Gene: 8672

Expression Profile of EIF4G3 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-106a-5p YES YES NO hsa-miR-106b-5p YES YES NO hsa-miR-129-5p YES YES YES hsa-miR-136-5p YES YES NO hsa-miR-17-5p YES YES NO hsa-miR-186-5p YES YES NO hsa-miR-193a-3p YES YES NO hsa-miR-193b-3p YES YES NO hsa-miR-20a-5p YES YES NO hsa-miR-20b-5p YES YES NO hsa-miR-217 YES YES NO hsa-miR-300 YES YES YES hsa-miR-335-5p YES YES NO hsa-miR-340-5p YES YES NO hsa-miR-375 YES YES YES hsa-miR-378a-3p YES YES YES hsa-miR-381-3p YES YES YES hsa-miR-382-5p YES YES NO hsa-miR-422a YES YES YES hsa-miR-495-3p YES YES NO hsa-miR-496 YES YES NO hsa-miR-519d-3p YES YES NO hsa-miR-520f-3p YES NO YES hsa-miR-532-3p YES NO YES hsa-miR-543 YES YES NO hsa-miR-758-3p YES YES NO hsa-miR-93-5p YES YES NO Display: