ctcRbase

Entry Detail

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General Information

Database ID: BRCA24771 Cancer Type: breast cancer Dataset: GSE41245 CTCs/CTM Isolation Method: CTC-Chip

Gene Information

ncRNA Symbol: HHIP Full Name: hedgehog interacting protein Category: mRNA Synonyms: HIP Chromosome: chr4 Strand: + Coordinate: Start Site(bp): 144646021 End Site(bp): 144745271 Gene Summary: This gene encodes a member of the hedgehog-interacting protein (HHIP) family. The hedgehog (HH) proteins are evolutionarily conserved protein, which are important morphogens for a wide range of developmental processes, including anteroposterior patterns of limbs and regulation of left-right asymmetry in embryonic development. Multiple cell-surface receptors are responsible for transducing and/or regulating HH signals. The HHIP encoded by this gene is a highly conserved, vertebrate-specific inhibitor of HH signaling. It interacts with all three HH family members, SHH, IHH and DHH. Two single nucleotide polymorphisms (SNPs) near this gene are significantly associated with risk of chronic obstructive pulmonary disease (COPD). A single nucleotide polymorphism in this gene is also strongly associated with human height.[provided by RefSeq, Feb 2011] External Links: Ensembl ID: ENSG00000164161 HGNC ID: HGNC:14866 Entrez Gene: 64399

Expression Profile of HHIP Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-153-3p YES YES NO hsa-miR-329-3p YES NO YES hsa-miR-362-3p YES NO YES hsa-miR-365a-3p YES YES YES hsa-miR-448 YES YES NO hsa-miR-495-3p YES YES NO Display: