ctcRbase

Entry Detail

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General Information

Database ID: BRCA24793 Cancer Type: breast cancer Dataset: GSE109761 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: SLC22A5 Full Name: solute carrier family 22 member 5 Category: mRNA Synonyms: CDSP|OCTN2 Chromosome: chr5 Strand: + Coordinate: Start Site(bp): 132369752 End Site(bp): 132395614 Gene Summary: Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. The encoded protein is a plasma integral membrane protein which functions both as an organic cation transporter and as a sodium-dependent high affinity carnitine transporter. The encoded protein is involved in the active cellular uptake of carnitine. Mutations in this gene are the cause of systemic primary carnitine deficiency (CDSP), an autosomal recessive disorder manifested early in life by hypoketotic hypoglycemia and acute metabolic decompensation, and later in life by skeletal myopathy or cardiomyopathy. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2015] External Links: Ensembl ID: ENSG00000197375 HGNC ID: HGNC:10969 Entrez Gene: 6584

Expression Profile of SLC22A5 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-124-3p YES YES YES hsa-miR-1271-5p YES YES YES hsa-miR-129-5p YES YES NO hsa-miR-1297 YES YES NO hsa-miR-138-5p YES YES NO hsa-miR-145-5p YES YES NO hsa-miR-148a-3p YES YES NO hsa-miR-148b-3p YES YES NO hsa-miR-152-3p YES YES NO hsa-miR-208a-3p YES YES NO hsa-miR-23a-3p YES YES NO hsa-miR-23b-3p YES YES NO hsa-miR-26a-5p YES YES NO hsa-miR-26b-5p YES YES NO hsa-miR-302a-3p YES YES YES hsa-miR-302b-3p YES YES YES hsa-miR-302c-3p YES YES YES hsa-miR-302d-3p YES YES YES hsa-miR-302e YES YES YES hsa-miR-30a-5p YES YES YES hsa-miR-30b-5p YES YES YES hsa-miR-30c-5p YES YES YES hsa-miR-30d-5p YES YES YES hsa-miR-30e-5p YES YES YES hsa-miR-329-3p YES NO NO hsa-miR-342-3p YES YES NO hsa-miR-362-3p YES NO NO hsa-miR-372-3p YES YES YES hsa-miR-373-3p YES YES YES hsa-miR-377-3p YES YES NO hsa-miR-382-5p YES YES NO hsa-miR-383-5p YES YES YES hsa-miR-411-5p YES YES NO hsa-miR-425-5p YES YES NO hsa-miR-495-3p YES YES NO hsa-miR-506-3p YES YES NO hsa-miR-520a-3p YES YES YES hsa-miR-520b YES YES YES hsa-miR-520c-3p YES YES YES hsa-miR-520d-3p YES YES YES hsa-miR-520e YES YES YES hsa-miR-96-5p YES YES YES Display: