Entry Detail



General Information

Database ID:BRCA25278
Cancer Type:breast cancer
Dataset:GSE109761
CTCs/CTM Isolation Method:microfluidics immunofluorescence



Gene Information

ncRNA Symbol:CREM
Full Name:cAMP responsive element modulator
Category:mRNA
Synonyms:CREM-2|ICER|hCREM-2
Chromosome:chr10
Strand:+
Coordinate:
Start Site(bp):35126791End Site(bp):35212958
Gene Summary:This gene encodes a bZIP transcription factor that binds to the cAMP responsive element found in many viral and cellular promoters. It is an important component of cAMP-mediated signal transduction during the spermatogenetic cycle, as well as other complex processes. Alternative promoter and translation initiation site usage allows this gene to exert spatial and temporal specificity to cAMP responsiveness. Multiple alternatively spliced transcript variants encoding several different isoforms have been found for this gene, with some of them functioning as activators and some as repressors of transcription. [provided by RefSeq, Jul 2008]
External Links:
Ensembl ID:ENSG00000095794
HGNC ID:HGNC:2352
Entrez Gene:1390



Expression Profile of CREM Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-let-7a-5p
YES
YES
NO
hsa-let-7b-5p
YES
YES
NO
hsa-let-7c-5p
YES
YES
NO
hsa-let-7d-5p
YES
YES
NO
hsa-let-7e-5p
YES
YES
NO
hsa-let-7f-5p
YES
YES
NO
hsa-let-7g-5p
YES
YES
NO
hsa-let-7i-5p
YES
YES
NO
hsa-miR-101-3p
YES
YES
NO
hsa-miR-106a-5p
YES
YES
NO
hsa-miR-106b-5p
YES
YES
NO
hsa-miR-128-3p
YES
YES
NO
hsa-miR-129-5p
YES
YES
NO
hsa-miR-130a-3p
YES
YES
NO
hsa-miR-130b-3p
YES
YES
NO
hsa-miR-137
YES
YES
NO
hsa-miR-1-3p
YES
YES
YES
hsa-miR-142-3p
YES
YES
NO
hsa-miR-144-3p
YES
YES
NO
hsa-miR-153-3p
YES
YES
YES
hsa-miR-155-5p
YES
YES
NO
hsa-miR-17-5p
YES
YES
NO
hsa-miR-186-5p
YES
YES
NO
hsa-miR-205-5p
YES
YES
NO
hsa-miR-206
YES
YES
YES
hsa-miR-20a-5p
YES
YES
NO
hsa-miR-20b-5p
YES
YES
NO
hsa-miR-25-3p
YES
YES
NO
hsa-miR-29a-3p
YES
YES
NO
hsa-miR-29b-3p
YES
YES
NO
hsa-miR-29c-3p
YES
YES
NO
hsa-miR-301a-3p
YES
YES
NO
hsa-miR-301b-3p
YES
YES
NO
hsa-miR-30a-5p
YES
YES
NO
hsa-miR-30b-5p
YES
YES
NO
hsa-miR-30c-5p
YES
YES
NO
hsa-miR-30d-5p
YES
YES
NO
hsa-miR-30e-5p
YES
YES
NO
hsa-miR-32-5p
YES
YES
NO
hsa-miR-33a-5p
YES
YES
NO
hsa-miR-33b-5p
YES
YES
NO
hsa-miR-363-3p
YES
YES
NO
hsa-miR-365a-3p
YES
YES
NO
hsa-miR-367-3p
YES
YES
NO
hsa-miR-376c-3p
YES
YES
NO
hsa-miR-381-3p
YES
YES
NO
hsa-miR-384
YES
YES
NO
hsa-miR-411-5p
YES
YES
NO
hsa-miR-425-5p
YES
YES
NO
hsa-miR-448
YES
YES
NO
hsa-miR-454-3p
YES
YES
NO
hsa-miR-519d-3p
YES
YES
NO
hsa-miR-543
YES
YES
NO
hsa-miR-613
YES
YES
YES
hsa-miR-92a-3p
YES
YES
NO
hsa-miR-92b-3p
YES
YES
NO
hsa-miR-93-5p
YES
YES
NO
hsa-miR-98-5p
YES
YES
NO
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