Entry Detail



General Information

Database ID:BRCA25487
Cancer Type:breast cancer
Dataset:GSE111065
CTCs/CTM Isolation Method:microfluidics immunofluorescence



Gene Information

ncRNA Symbol:POFUT2
Full Name:protein O-fucosyltransferase 2
Category:mRNA
Synonyms:C21orf80|FUT13
Chromosome:chr21
Strand:-
Coordinate:
Start Site(bp):45263928End Site(bp):45287898
Gene Summary:Fucose is typically found as a terminal modification of branched chain glycoconjugates, but it also exists in direct O-linkage to serine or threonine residues within cystine knot motifs in epidermal growth factor (EGF; MIM 131530)-like repeats or thrombospondin (THBS; see MIM 188060) type-1 repeats. POFUT2 is an O-fucosyltransferase that use THBS type-1 repeats as substrates (Luo et al., 2006 [PubMed 16464857]).[supplied by OMIM, Mar 2008]
External Links:
Ensembl ID:ENSG00000186866
HGNC ID:HGNC:14683
Entrez Gene:23275



Expression Profile of POFUT2 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-10a-5p
YES
YES
NO
hsa-miR-10b-5p
YES
YES
NO
hsa-miR-124-3p
YES
YES
NO
hsa-miR-186-5p
YES
YES
YES
hsa-miR-224-5p
YES
YES
NO
hsa-miR-27a-3p
YES
YES
NO
hsa-miR-27b-3p
YES
YES
NO
hsa-miR-320a
YES
YES
NO
hsa-miR-320b
YES
YES
NO
hsa-miR-339-5p
YES
YES
NO
hsa-miR-371a-5p
YES
YES
NO
hsa-miR-451a
YES
YES
NO
hsa-miR-506-3p
YES
YES
NO
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