ctcRbase

Entry Detail

---



General Information

Database ID: BRCA26260 Cancer Type: breast cancer Dataset: GSE55807 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: TOPBP1 Full Name: DNA topoisomerase II binding protein 1 Category: mRNA Synonyms: Dpb11|TOP2BP1 Chromosome: chr3 Strand: - Coordinate: Start Site(bp): 133598175 End Site(bp): 133661893 Gene Summary: This gene encodes a binding protein which interacts with the C-terminal region of topoisomerase II beta. This interaction suggests a supportive role for this protein in the catalytic reactions of topoisomerase II beta through transient breakages of DNA strands. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000163781 HGNC ID: HGNC:17008 Entrez Gene: 11073

Expression Profile of TOPBP1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-let-7a-5p YES YES NO hsa-let-7b-5p YES YES NO hsa-let-7c-5p YES YES NO hsa-let-7d-5p YES YES NO hsa-let-7e-5p YES YES NO hsa-let-7f-5p YES YES NO hsa-let-7g-5p YES YES NO hsa-let-7i-5p YES YES NO hsa-miR-124-3p YES YES NO hsa-miR-1271-5p YES YES NO hsa-miR-128-3p YES YES NO hsa-miR-132-3p YES YES NO hsa-miR-139-5p YES YES NO hsa-miR-181a-5p YES YES YES hsa-miR-181b-5p YES YES YES hsa-miR-181c-5p YES YES YES hsa-miR-181d-5p YES YES YES hsa-miR-182-5p YES YES YES hsa-miR-212-3p YES YES NO hsa-miR-23a-3p YES YES NO hsa-miR-23b-3p YES YES NO hsa-miR-27a-3p YES YES YES hsa-miR-27b-3p YES YES YES hsa-miR-329-3p YES YES YES hsa-miR-362-3p YES YES YES hsa-miR-450a-5p YES YES NO hsa-miR-494-3p YES YES NO hsa-miR-506-3p YES YES NO hsa-miR-96-5p YES YES NO hsa-miR-98-5p YES YES NO Display: