ctcRbase

Entry Detail

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General Information

Database ID: BRCA26307 Cancer Type: breast cancer Dataset: GSE41245 CTCs/CTM Isolation Method: CTC-Chip

Gene Information

ncRNA Symbol: IQSEC2 Full Name: IQ motif and Sec7 domain 2 Category: mRNA Synonyms: BRAG1|IQ-ArfGEF|MRX1|MRX18|MRX78 Chromosome: chrX Strand: - Coordinate: Start Site(bp): 53225828 End Site(bp): 53321328 Gene Summary: This gene encodes a guanine nucleotide exchange factor for the ARF family of small GTP-binding proteins. The encoded protein is a component of the postsynaptic density at excitatory synapses, and may play a critical role in cytoskeletal and synaptic organization through the activation of selected ARF substrates including ARF1 and ARF6. Mutations in this gene have been implicated in nonsyndromic X-linked cognitive disability. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2011] External Links: Ensembl ID: ENSG00000124313 HGNC ID: HGNC:29059 Entrez Gene: 23096

Expression Profile of IQSEC2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-106a-5p YES YES YES hsa-miR-106b-5p YES YES YES hsa-miR-134-5p YES NO YES hsa-miR-138-5p YES NO YES hsa-miR-147a YES NO NO hsa-miR-17-5p YES YES YES hsa-miR-20a-5p YES YES YES hsa-miR-20b-5p YES YES YES hsa-miR-28-5p YES YES YES hsa-miR-302a-3p YES YES YES hsa-miR-302b-3p YES YES YES hsa-miR-302c-3p YES YES YES hsa-miR-302d-3p YES YES YES hsa-miR-302e YES YES YES hsa-miR-31-5p YES YES YES hsa-miR-33a-5p YES YES YES hsa-miR-33b-5p YES YES YES hsa-miR-370-3p YES NO YES hsa-miR-372-3p YES YES YES hsa-miR-373-3p YES YES YES hsa-miR-519d-3p YES YES YES hsa-miR-520a-3p YES YES YES hsa-miR-520b YES YES YES hsa-miR-520c-3p YES YES YES hsa-miR-520d-3p YES YES YES hsa-miR-520e YES YES YES hsa-miR-520f-3p YES NO YES hsa-miR-541-3p YES NO NO hsa-miR-654-5p YES NO NO hsa-miR-708-5p YES YES YES hsa-miR-93-5p YES YES YES Display: