ctcRbase

Entry Detail

---



General Information

Database ID: BRCA26439 Cancer Type: breast cancer Dataset: GSE109761 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: ACVR1B Full Name: activin A receptor type 1B Category: mRNA Synonyms: ACTRIB|ACVRLK4|ALK4|SKR2 Chromosome: chr12 Strand: + Coordinate: Start Site(bp): 51951667 End Site(bp): 51997078 Gene Summary: This gene encodes an activin A type IB receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I and two type II receptors. This protein is a type I receptor which is essential for signaling. Mutations in this gene are associated with pituitary tumors. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Jun 2010] External Links: Ensembl ID: ENSG00000135503 HGNC ID: HGNC:172 Entrez Gene: 91

Expression Profile of ACVR1B Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-let-7a-5p YES NO YES hsa-let-7b-5p YES NO YES hsa-let-7c-5p YES NO YES hsa-let-7d-5p YES NO YES hsa-let-7e-5p YES NO YES hsa-let-7f-5p YES NO YES hsa-let-7g-5p YES NO YES hsa-let-7i-5p YES NO YES hsa-miR-106a-5p YES NO YES hsa-miR-106b-5p YES NO YES hsa-miR-135a-5p YES YES YES hsa-miR-135b-5p YES YES YES hsa-miR-143-3p YES YES NO hsa-miR-145-5p YES NO YES hsa-miR-148a-3p YES YES NO hsa-miR-148b-3p YES YES NO hsa-miR-150-5p YES YES YES hsa-miR-152-3p YES YES NO hsa-miR-153-3p YES YES YES hsa-miR-17-5p YES NO YES hsa-miR-181c-5p YES YES NO hsa-miR-182-5p YES YES NO hsa-miR-197-3p YES YES NO hsa-miR-199a-5p YES YES YES hsa-miR-199b-5p YES YES YES hsa-miR-20a-5p YES NO YES hsa-miR-20b-5p YES NO YES hsa-miR-210-3p YES YES NO hsa-miR-22-3p YES NO YES hsa-miR-24-3p YES NO YES hsa-miR-326 YES YES NO hsa-miR-330-5p YES YES NO hsa-miR-362-3p YES NO NO hsa-miR-371a-5p YES YES YES hsa-miR-383-5p YES YES YES hsa-miR-384 YES YES YES hsa-miR-425-5p YES YES NO hsa-miR-448 YES YES YES hsa-miR-491-5p YES YES NO hsa-miR-495-3p YES YES YES hsa-miR-519d-3p YES NO YES hsa-miR-543 YES YES NO hsa-miR-582-5p YES NO YES hsa-miR-653-5p YES YES NO hsa-miR-758-3p YES YES NO hsa-miR-876-5p YES YES NO hsa-miR-93-5p YES NO YES hsa-miR-9-5p YES NO YES hsa-miR-98-5p YES NO YES Display: