ctcRbase

Entry Detail

---



General Information

Database ID: BRCA26668 Cancer Type: breast cancer Dataset: GSE111065 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: ADCY6 Full Name: adenylate cyclase 6 Category: mRNA Synonyms: AC6|LCCS8 Chromosome: chr12 Strand: - Coordinate: Start Site(bp): 48766194 End Site(bp): 48789037 Gene Summary: This gene encodes a member of the adenylyl cyclase family of proteins, which are required for the synthesis of cyclic AMP. All members of this family have an intracellular N-terminus, a tandem repeat of six transmembrane domains separated by a cytoplasmic loop, and a C-terminal cytoplasmic domain. The two cytoplasmic regions bind ATP and form the catalytic core of the protein. Adenylyl cyclases are important effectors of transmembrane signaling pathways and are regulated by the activity of G protein coupled receptor signaling. This protein belongs to a small subclass of adenylyl cyclase proteins that are functionally related and are inhibited by protein kinase A, calcium ions and nitric oxide. A mutation in this gene is associated with arthrogryposis multiplex congenita. [provided by RefSeq, May 2015] External Links: Ensembl ID: ENSG00000174233 HGNC ID: HGNC:237 Entrez Gene: 112

Expression Profile of ADCY6 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-101-3p YES YES YES hsa-miR-1271-5p YES YES NO hsa-miR-128-3p YES NO YES hsa-miR-140-5p YES YES YES hsa-miR-182-5p YES YES YES hsa-miR-197-3p YES YES NO hsa-miR-204-5p NO YES YES hsa-miR-211-5p NO YES YES hsa-miR-224-5p YES YES YES hsa-miR-27a-3p YES YES YES hsa-miR-27b-3p YES YES YES hsa-miR-302a-3p YES YES NO hsa-miR-302b-3p YES YES NO hsa-miR-302c-3p YES YES NO hsa-miR-302d-3p YES YES NO hsa-miR-302e YES YES NO hsa-miR-31-5p YES YES YES hsa-miR-323a-3p YES NO YES hsa-miR-340-5p YES NO YES hsa-miR-372-3p YES YES NO hsa-miR-373-3p YES YES NO hsa-miR-376c-3p YES YES NO hsa-miR-409-5p YES NO YES hsa-miR-490-3p YES YES NO hsa-miR-494-3p YES YES YES hsa-miR-520a-3p YES YES NO hsa-miR-520b YES YES NO hsa-miR-520c-3p YES YES NO hsa-miR-520d-3p YES YES NO hsa-miR-520e YES YES NO hsa-miR-873-5p YES YES NO hsa-miR-9-5p YES NO YES hsa-miR-96-5p YES YES NO Display: