ctcRbase

Entry Detail

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General Information

Database ID: BRCA27974 Cancer Type: breast cancer Dataset: GSE111065 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: ARHGEF18 Full Name: Rho/Rac guanine nucleotide exchange factor 18 Category: mRNA Synonyms: P114-RhoGEF|RP78 Chromosome: chr19 Strand: + Coordinate: Start Site(bp): 7395113 End Site(bp): 7472477 Gene Summary: Rho GTPases are GTP binding proteins that regulate a wide spectrum of cellular functions. These cellular processes include cytoskeletal rearrangements, gene transcription, cell growth and motility. Activation of Rho GTPases is under the direct control of guanine nucleotide exchange factors (GEFs). The protein encoded by this gene is a guanine nucleotide exchange factor and belongs to the Rho GTPase GEF family. Family members share a common feature, a Dbl (DH) homology domain followed by a pleckstrin (PH) homology domain. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Nov 2018] External Links: Ensembl ID: ENSG00000104880 HGNC ID: HGNC:17090 Entrez Gene: 23370

Expression Profile of ARHGEF18 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-106a-5p YES YES YES hsa-miR-106b-5p YES YES YES hsa-miR-137 YES YES YES hsa-miR-1-3p YES NO YES hsa-miR-141-3p YES YES YES hsa-miR-17-5p YES YES YES hsa-miR-183-5p YES YES YES hsa-miR-200a-3p YES YES YES hsa-miR-206 YES NO YES hsa-miR-20a-5p YES YES YES hsa-miR-20b-5p YES YES YES hsa-miR-302a-3p YES YES YES hsa-miR-302b-3p YES YES YES hsa-miR-302c-3p YES YES YES hsa-miR-302d-3p YES YES YES hsa-miR-302e YES YES YES hsa-miR-372-3p YES YES YES hsa-miR-373-3p YES YES YES hsa-miR-519d-3p YES YES YES hsa-miR-520a-3p YES YES YES hsa-miR-520b YES YES YES hsa-miR-520c-3p YES YES YES hsa-miR-520d-3p YES YES YES hsa-miR-520e YES YES YES hsa-miR-613 YES NO YES hsa-miR-93-5p YES YES YES Display: