ctcRbase

Entry Detail

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General Information

Database ID: BRCA28051 Cancer Type: breast cancer Dataset: GSE41245 CTCs/CTM Isolation Method: CTC-Chip

Gene Information

ncRNA Symbol: PRRX1 Full Name: paired related homeobox 1 Category: mRNA Synonyms: AGOTC|PHOX1|PMX1|PRX-1|PRX1 Chromosome: chr1 Strand: + Coordinate: Start Site(bp): 170662728 End Site(bp): 170739419 Gene Summary: The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription co-activator, enhancing the DNA-binding activity of serum response factor, a protein required for the induction of genes by growth and differentiation factors. The protein regulates muscle creatine kinase, indicating a role in the establishment of diverse mesodermal muscle types. Alternative splicing yields two isoforms that differ in abundance and expression patterns. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000116132 HGNC ID: HGNC:9142 Entrez Gene: 5396

Expression Profile of PRRX1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-let-7a-5p YES YES YES hsa-let-7b-5p YES YES YES hsa-let-7c-5p YES YES YES hsa-let-7d-5p YES YES YES hsa-let-7e-5p YES YES YES hsa-let-7f-5p YES YES YES hsa-let-7g-5p YES YES YES hsa-let-7i-5p YES YES YES hsa-miR-106a-5p YES YES NO hsa-miR-106b-5p YES YES NO hsa-miR-124-3p YES YES YES hsa-miR-1271-5p YES YES YES hsa-miR-153-3p YES YES NO hsa-miR-154-5p YES YES NO hsa-miR-17-5p YES YES NO hsa-miR-182-5p YES YES YES hsa-miR-186-5p YES YES NO hsa-miR-204-5p YES YES YES hsa-miR-20a-5p YES YES NO hsa-miR-20b-5p YES YES NO hsa-miR-211-5p YES YES YES hsa-miR-224-5p YES YES NO hsa-miR-299-3p YES YES NO hsa-miR-300 YES YES NO hsa-miR-302a-3p YES YES YES hsa-miR-302b-3p YES YES YES hsa-miR-302c-3p YES YES YES hsa-miR-302d-3p YES YES YES hsa-miR-302e YES YES YES hsa-miR-30a-5p YES NO YES hsa-miR-30b-5p YES NO YES hsa-miR-30c-5p YES NO YES hsa-miR-30d-5p YES NO YES hsa-miR-30e-5p YES NO YES hsa-miR-330-3p YES NO YES hsa-miR-362-3p YES NO NO hsa-miR-372-3p YES YES YES hsa-miR-373-3p YES YES YES hsa-miR-381-3p YES YES NO hsa-miR-383-5p YES YES NO hsa-miR-410-3p YES YES NO hsa-miR-485-5p YES YES NO hsa-miR-506-3p YES YES NO hsa-miR-519d-3p YES YES NO hsa-miR-520a-3p YES YES YES hsa-miR-520b YES YES YES hsa-miR-520c-3p YES YES YES hsa-miR-520d-3p YES YES YES hsa-miR-520e YES YES YES hsa-miR-541-3p YES NO NO hsa-miR-542-3p YES YES NO hsa-miR-654-5p YES NO NO hsa-miR-874-3p YES YES YES hsa-miR-93-5p YES YES NO hsa-miR-9-5p YES YES YES hsa-miR-96-5p YES YES YES hsa-miR-98-5p YES YES YES Display: