Entry Detail



General Information

Database ID:BRCA28066
Cancer Type:breast cancer
Dataset:GSE55807
CTCs/CTM Isolation Method:CTC-iChip



Gene Information

ncRNA Symbol:CYP1B1
Full Name:cytochrome P450 family 1 subfamily B member 1
Category:mRNA
Synonyms:ASGD6|CP1B|CYPIB1|GLC3A|P4501B1
Chromosome:chr2
Strand:-
Coordinate:
Start Site(bp):38066973End Site(bp):38109902
Gene Summary:This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The enzyme encoded by this gene localizes to the endoplasmic reticulum and metabolizes procarcinogens such as polycyclic aromatic hydrocarbons and 17beta-estradiol. Mutations in this gene have been associated with primary congenital glaucoma; therefore it is thought that the enzyme also metabolizes a signaling molecule involved in eye development, possibly a steroid. [provided by RefSeq, Jul 2008]
External Links:
Ensembl ID:ENSG00000138061
HGNC ID:HGNC:2597
Entrez Gene:1545



Expression Profile of CYP1B1 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-129-5p
YES
YES
NO
hsa-miR-135a-5p
YES
YES
NO
hsa-miR-135b-5p
YES
YES
NO
hsa-miR-154-5p
YES
YES
NO
hsa-miR-15a-5p
YES
YES
NO
hsa-miR-15b-5p
YES
YES
NO
hsa-miR-16-5p
YES
YES
NO
hsa-miR-182-5p
YES
YES
YES
hsa-miR-195-5p
YES
YES
NO
hsa-miR-200b-3p
YES
YES
NO
hsa-miR-200c-3p
YES
YES
NO
hsa-miR-204-5p
YES
YES
NO
hsa-miR-211-5p
YES
YES
NO
hsa-miR-221-3p
YES
YES
NO
hsa-miR-222-3p
YES
YES
NO
hsa-miR-27a-3p
YES
NO
YES
hsa-miR-27b-3p
YES
NO
YES
hsa-miR-300
YES
YES
NO
hsa-miR-362-5p
YES
NO
YES
hsa-miR-374a-5p
YES
YES
NO
hsa-miR-374b-5p
YES
YES
NO
hsa-miR-377-3p
YES
YES
NO
hsa-miR-381-3p
YES
YES
NO
hsa-miR-410-3p
YES
YES
NO
hsa-miR-424-5p
YES
YES
NO
hsa-miR-429
YES
YES
NO
hsa-miR-433-3p
YES
YES
NO
hsa-miR-488-3p
YES
YES
NO
hsa-miR-490-3p
YES
YES
NO
hsa-miR-495-3p
YES
YES
NO
hsa-miR-497-5p
YES
YES
NO
hsa-miR-599
YES
YES
NO
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