ctcRbase

Entry Detail

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General Information

Database ID: BRCA28561 Cancer Type: breast cancer Dataset: GSE111065 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: EGFR Full Name: epidermal growth factor receptor Category: mRNA Synonyms: ERBB|ERBB1|HER1|NISBD2|PIG61|mENA Chromosome: chr7 Strand: + Coordinate: Start Site(bp): 55019021 End Site(bp): 55211628 Gene Summary: The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. [provided by RefSeq, Jun 2016] External Links: Ensembl ID: ENSG00000146648 HGNC ID: HGNC:3236 Entrez Gene: 1956

Expression Profile of EGFR Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-103a-3p YES YES NO hsa-miR-107 YES YES NO hsa-miR-129-5p YES YES NO hsa-miR-133a-3p YES YES NO hsa-miR-133b YES YES NO hsa-miR-134-5p YES YES NO hsa-miR-141-3p YES YES NO hsa-miR-147a YES NO NO hsa-miR-149-5p YES YES NO hsa-miR-155-5p YES YES NO hsa-miR-200a-3p YES YES NO hsa-miR-27a-3p YES YES NO hsa-miR-27b-3p YES YES NO hsa-miR-299-3p YES YES NO hsa-miR-302a-3p YES YES NO hsa-miR-302b-3p YES YES NO hsa-miR-302c-3p YES YES NO hsa-miR-302d-3p YES YES NO hsa-miR-302e YES YES NO hsa-miR-33a-5p YES YES NO hsa-miR-33b-5p YES YES NO hsa-miR-370-3p YES YES NO hsa-miR-372-3p YES YES NO hsa-miR-373-3p YES YES NO hsa-miR-450a-5p YES YES NO hsa-miR-455-5p YES YES NO hsa-miR-491-5p YES YES NO hsa-miR-520a-3p YES YES NO hsa-miR-520b YES YES NO hsa-miR-520c-3p YES YES NO hsa-miR-520d-3p YES YES NO hsa-miR-520e YES YES NO hsa-miR-7-5p YES YES NO hsa-miR-875-5p YES YES YES Display: