Entry Detail



General Information

Database ID:BRCA28569
Cancer Type:breast cancer
Dataset:GSE67939
CTCs/CTM Isolation Method:Cluster-Chip



Gene Information

ncRNA Symbol:LMO2
Full Name:LIM domain only 2
Category:mRNA
Synonyms:LMO-2|RBTN2|RBTNL1|RHOM2|TTG2
Chromosome:chr11
Strand:-
Coordinate:
Start Site(bp):33858576End Site(bp):33892289
Gene Summary:LMO2 encodes a cysteine-rich, two LIM-domain protein that is required for yolk sac erythropoiesis. The LMO2 protein has a central and crucial role in hematopoietic development and is highly conserved. The LMO2 transcription start site is located approximately 25 kb downstream from the 11p13 T-cell translocation cluster (11p13 ttc), where a number T-cell acute lymphoblastic leukemia-specific translocations occur. Alternative splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Nov 2008]
External Links:
Ensembl ID:ENSG00000135363
HGNC ID:HGNC:6642
Entrez Gene:4005



Expression Profile of LMO2 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-132-3p
YES
YES
NO
hsa-miR-212-3p
YES
YES
NO
hsa-miR-223-3p
YES
YES
YES
hsa-miR-25-3p
YES
YES
YES
hsa-miR-32-5p
YES
YES
YES
hsa-miR-363-3p
YES
YES
YES
hsa-miR-367-3p
YES
YES
YES
hsa-miR-382-5p
YES
YES
NO
hsa-miR-494-3p
YES
YES
NO
hsa-miR-92a-3p
YES
YES
YES
hsa-miR-92b-3p
YES
YES
YES
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