Entry Detail



General Information

Database ID:BRCA29068
Cancer Type:breast cancer
Dataset:GSE41245
CTCs/CTM Isolation Method:CTC-Chip



Gene Information

ncRNA Symbol:CORIN
Full Name:corin, serine peptidase
Category:mRNA
Synonyms:ATC2|CRN|Lrp4|PEE5|TMPRSS10
Chromosome:chr4
Strand:-
Coordinate:
Start Site(bp):47593998End Site(bp):47838106
Gene Summary:This gene encodes a member of the type II transmembrane serine protease class of the trypsin superfamily. Members of this family are composed of multiple structurally distinct domains. The encoded protein converts pro-atrial natriuretic peptide to biologically active atrial natriuretic peptide, a cardiac hormone that regulates blood volume and pressure. This protein may also function as a pro-brain-type natriuretic peptide convertase. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2013]
External Links:
Ensembl ID:ENSG00000145244
HGNC ID:HGNC:19012
Entrez Gene:10699



Expression Profile of CORIN Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-141-3p
YES
YES
NO
hsa-miR-186-5p
YES
YES
NO
hsa-miR-200a-3p
YES
YES
NO
hsa-miR-491-5p
YES
YES
NO
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