Entry Detail



General Information

Database ID:BRCA29123
Cancer Type:breast cancer
Dataset:GSE41245
CTCs/CTM Isolation Method:CTC-Chip



Gene Information

ncRNA Symbol:TBX19
Full Name:T-box 19
Category:mRNA
Synonyms:TBS19|TPIT|dJ747L4.1
Chromosome:chr1
Strand:+
Coordinate:
Start Site(bp):168281040End Site(bp):168314426
Gene Summary:This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. Mutations in this gene were found in patients with isolated deficiency of pituitary POMC-derived ACTH, suggesting an essential role for this gene in differentiation of the pituitary POMC lineage. ACTH deficiency is characterized by adrenal insufficiency symptoms such as weight loss, lack of appetite (anorexia), weakness, nausea, vomiting, and low blood pressure. [provided by RefSeq, Jul 2008]
External Links:
Ensembl ID:ENSG00000143178
HGNC ID:HGNC:11596
Entrez Gene:9095



Expression Profile of TBX19 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-106a-5p
YES
YES
NO
hsa-miR-106b-5p
YES
YES
NO
hsa-miR-130a-3p
YES
YES
NO
hsa-miR-130b-3p
YES
YES
NO
hsa-miR-17-5p
YES
YES
NO
hsa-miR-20a-5p
YES
YES
NO
hsa-miR-20b-5p
YES
YES
NO
hsa-miR-301a-3p
YES
YES
NO
hsa-miR-301b-3p
YES
YES
NO
hsa-miR-454-3p
YES
YES
NO
hsa-miR-519d-3p
YES
YES
NO
hsa-miR-93-5p
YES
YES
NO
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