ctcRbase

Entry Detail

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General Information

Database ID: BRCA29225 Cancer Type: breast cancer Dataset: GSE41245 CTCs/CTM Isolation Method: CTC-Chip

Gene Information

ncRNA Symbol: GDF11 Full Name: growth differentiation factor 11 Category: mRNA Synonyms: BMP-11|BMP11 Chromosome: chr12 Strand: + Coordinate: Start Site(bp): 55743280 End Site(bp): 55757278 Gene Summary: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein plays a role in the development of the nervous and other organ systems, and may regulate aging. [provided by RefSeq, Aug 2016] External Links: Ensembl ID: ENSG00000135414 HGNC ID: HGNC:4216 Entrez Gene: 10220

Expression Profile of GDF11 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-106a-5p NO YES YES hsa-miR-106b-5p NO YES YES hsa-miR-128-3p NO YES YES hsa-miR-149-5p NO YES YES hsa-miR-17-5p NO YES YES hsa-miR-20a-5p NO YES YES hsa-miR-20b-5p NO YES YES hsa-miR-224-5p NO YES YES hsa-miR-24-3p NO YES YES hsa-miR-25-3p YES YES YES hsa-miR-300 NO YES YES hsa-miR-302a-3p NO YES YES hsa-miR-302b-3p NO YES YES hsa-miR-302c-3p NO YES YES hsa-miR-302d-3p NO YES YES hsa-miR-302e NO YES YES hsa-miR-32-5p YES YES YES hsa-miR-363-3p YES YES YES hsa-miR-367-3p YES YES YES hsa-miR-372-3p NO YES YES hsa-miR-373-3p NO YES YES hsa-miR-381-3p NO YES YES hsa-miR-519d-3p NO YES YES hsa-miR-520a-3p NO YES YES hsa-miR-520b NO YES YES hsa-miR-520c-3p NO YES YES hsa-miR-520d-3p NO YES YES hsa-miR-520e NO YES YES hsa-miR-874-3p NO YES YES hsa-miR-92a-3p YES YES YES hsa-miR-92b-3p YES YES YES hsa-miR-93-5p NO YES YES Display: