ctcRbase

Entry Detail

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General Information

Database ID: BRCA29429 Cancer Type: breast cancer Dataset: GSE41245 CTCs/CTM Isolation Method: CTC-Chip

Gene Information

ncRNA Symbol: FZD8 Full Name: frizzled class receptor 8 Category: mRNA Synonyms: FZ-8|hFZ8 Chromosome: chr10 Strand: - Coordinate: Start Site(bp): 35638249 End Site(bp): 35642278 Gene Summary: This intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This gene is highly expressed in two human cancer cell lines, indicating that it may play a role in several types of cancer. The crystal structure of the extracellular cysteine-rich domain of a similar mouse protein has been determined. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000177283 HGNC ID: HGNC:4046 Entrez Gene: 8325

Expression Profile of FZD8 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-100-5p YES YES YES hsa-miR-124-3p YES NO YES hsa-miR-18a-5p YES YES NO hsa-miR-18b-5p YES YES NO hsa-miR-19a-3p YES YES NO hsa-miR-19b-3p YES YES NO hsa-miR-200b-3p YES YES NO hsa-miR-200c-3p YES YES NO hsa-miR-208a-3p YES YES YES hsa-miR-208b-3p YES YES YES hsa-miR-224-5p YES YES NO hsa-miR-329-3p YES YES NO hsa-miR-340-5p YES YES NO hsa-miR-362-3p YES YES NO hsa-miR-410-3p YES YES YES hsa-miR-429 YES YES NO hsa-miR-491-5p YES YES NO hsa-miR-495-3p YES YES YES hsa-miR-499a-5p YES YES YES hsa-miR-9-5p YES YES NO hsa-miR-99a-5p YES YES YES hsa-miR-99b-5p YES YES YES Display: