ctcRbase

Entry Detail

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General Information

Database ID: BRCA29627 Cancer Type: breast cancer Dataset: GSE55807 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: PPP1R3C Full Name: protein phosphatase 1 regulatory subunit 3C Category: mRNA Synonyms: PPP1R5|PTG Chromosome: chr10 Strand: - Coordinate: Start Site(bp): 91628442 End Site(bp): 91633054 Gene Summary: This gene encodes a carbohydrate binding protein that is a subunit of the protein phosphatase 1 (PP1) complex. PP1 catalyzes reversible protein phosphorylation, which is important in a wide range of cellular activities. The encoded protein affects glycogen biosynthesis by activating glycogen synthase and limiting glycogen breakdown by reducing glycogen phosphorylase activity. DNA hypermethylation of this gene has been found in colorectal cancer patients. The encoded protein also interacts with the laforin protein, which is a protein tyrosine phosphatase implicated in Lafora disease. [provided by RefSeq, Sep 2016] External Links: Ensembl ID: ENSG00000119938 HGNC ID: HGNC:9293 Entrez Gene: 5507

Expression Profile of PPP1R3C Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-101-3p YES YES NO hsa-miR-144-3p YES YES NO hsa-miR-154-5p YES YES NO hsa-miR-181a-5p YES YES NO hsa-miR-181b-5p YES YES NO hsa-miR-181c-5p YES YES NO hsa-miR-183-5p YES YES NO hsa-miR-186-5p YES YES NO hsa-miR-217 YES YES NO hsa-miR-224-5p YES YES NO hsa-miR-33a-5p YES YES NO hsa-miR-33b-5p YES YES NO hsa-miR-374a-5p YES YES NO hsa-miR-374b-5p YES YES NO hsa-miR-377-3p YES YES NO hsa-miR-383-5p YES YES NO hsa-miR-411-5p YES YES NO hsa-miR-543 YES YES NO Display: