| ncRNA Symbol: | HOXB5 |
| Full Name: | homeobox B5 |
| Category: | mRNA |
| Synonyms: | HHO.C10|HOX2|HOX2A|HU-1|Hox2.1 |
| Chromosome: | chr17 |
| Strand: | - |
| Coordinate: | | Start Site(bp): | 48591257 | End Site(bp): | 48593961 |
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| Gene Summary: | This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in lung and gut development. Increased expression of this gene is associated with a distinct biologic subset of acute myeloid leukemia (AML) and the occurrence of bronchopulmonary sequestration (BPS) and congenital cystic adenomatoid malformation (CCAM) tissue. [provided by RefSeq, Jul 2008] |
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